Evidence map›Paper›PMID 40921736›Full record

ArticleSignal transduction and targeted therapy2025

Epidemiological and phylogenetic characteristics of human metapneumovirus in Beijing, China, 2014-2024.

Aihua Li, Cheng Gong, Liang Wang, Yuling Han, Lu Kang, Geng Hu, Jian Cao, Maozhong Li, Xuejiao Guan, Ming Luo and 5 more

Abstract read
In one paragraph

Article in Signal transduction and targeted therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Twenty-five years of human metapneumovirus research.Clinical microbiology reviews · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Molecular Evolution of theMicroorganisms · 2026
    Article
  10. Biosafety and health · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Aihua Li *Beijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
Cheng Gong *Beijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
Liang Wang *CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-Warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences (CAS), Beijing, China.ORCID 0000-0002-7897-8581
Yuling HanBeijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
Lu KangBeijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
Geng HuBeijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
Jian CaoCAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-Warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences (CAS), Beijing, China.
Maozhong LiBeijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
Xuejiao GuanBeijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
Ming LuoBeijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
Lei YuChildren's Hospital Affiliated to Capital Institute of Pediatrics, Beijing, China.
Yuchuan LiBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Fang HuangBeijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China.
George F GaoCAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-Warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences (CAS), Beijing, China. gaof@im.ac.cn.ORCID 0000-0002-3869-615X
Quanyi WangBeijing Key Laboratory of Surveillance, Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Research Center for Respiratory Infectious Diseases, Public Health Emergency Management Innovation Center, Beijing Center for Disease Prevention and Control, Beijing, China. wangqy@bjcdc.org.

Funding

Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) L242051
6 · The paper itself

Abstract

In November 2024, there was an unusual surge in human metapneumovirus (hMPV) infection cases in Beijing. We performed an epidemiological investigation among cases with acute respiratory tract infection (ARTI). We enrolled ARTI cases from 35 sentinel hospitals, collected samples and medical records, conducted comprehensive pathogen testing, sequenced target genes or whole genomes, and performed phylogenetic analysis. A total of 79,793 cases were included in this study from 2014 to 2024. The hMPV epidemic exhibited typical seasonality from December to April of the following year, with an overall positivity rate of hMPV of 1.6%. The positivity rate of hMPV was highest in the 0-4 year age group (3.4%) and remained relatively high (1.2%) among populations over 60 years of age. Genotypes A and B were cocirculated, with predominant genotypes alternating every two years. We identified two variants of A2c with 180 or 111 nucleotide duplications in the G gene since 2016, and the A2c

Indexed as

MetapneumovirusParamyxoviridae InfectionsPhylogenyRespiratory Tract InfectionsAdolescentAdultAgedBeijingChildChild, PreschoolFemaleGenome, ViralGenotypeHumansInfantInfant, Newborn

Identifiers

PMID40921736
PMCPMC12417542

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.