Evidence map›Paper›PMID 40921253›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2025

Full free-breathing cardiovascular magnetic resonance imaging: enhancing efficiency and image quality in clinical practice.

Kai Yang, Chen Cui, Fei Teng, Gang Yin, Jing An, Xinling Yang, Jinghui Li, Xiaoming Bi, Jianing Pang, Kelvin Chow and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Fully automated free-breathing cardiac magnetic resonance imaging at 3T: A prospective randomized study of image quality, efficiency, and workflow burden.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Article
  3. Cardiac function assessment with deep-learning-based automatic segmentation of free-running four-dimensional whole-heart cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kai YangDepartment of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.
Chen CuiDepartment of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.
Fei TengDepartment of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China; Department of Radiology, Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences, Shenzhen 518057, China.
Gang YinDepartment of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.
Jing AnSiemens Shenzhen Magnetic Resonance Ltd., Shenzhen 518057, China.
Xinling YangDepartment of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.
Jinghui LiDepartment of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.
Xiaoming BiSiemens Medical Solutions USA Inc., Chicago, Illinois, USA.
Jianing PangSiemens Medical Solutions USA Inc., Chicago, Illinois, USA.
Kelvin ChowSiemens Healthcare Ltd., Calgary, Alberta, Canada.
Shihua ZhaoDepartment of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.
Minjie LuDepartment of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China; Key Laboratory of Cardiovascular Imaging, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: coolkan@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConventional cardiovascular magnetic resonance (CMR) examinations require patients to repeatedly hold their breath, which can reduce examination efficiency and pose challenges for patients unable to do so. This study aimed to demonstrate the feasibility and effectiveness of a full free-breathing CMR protocol in clinical practice.

methodsPatients prospectively enrolled in this study underwent a full free-breathing CMR exam on a 3T scanner between June 1 and June 30, 2024. Acquisition time and image quality were assessed. Cine and flow imaging were compared with those acquired with the conventional breath-holding CMR protocol. Other sequences, including T1/T2 mapping and late gadolinium enhancement (LGE), were evaluated quantitatively and qualitatively, respectively. Group comparisons were performed using the Wilcoxon signed-rank test or paired t-test. Consistency was assessed using Kappa statistics, Bland-Altman statistics, intraclass correlation coefficient (ICC), and linear regression.

resultsA total of 211 patients were evaluated (median age: 53 years [IQR: 38-63]; range: 10-82 years; 145 men). The mean acquisition time for full free-breathing CMR was 22.6±3.7 min. The median image quality scores for cine and LGE images acquired with free-breathing CMR were 4 (IQR: 4-4) and 5 (IQR: 4-5), respectively. Compared with conventional breath-holding CMR, the end-diastolic volume (EDV), end-systolic volume (ESV), EDV index, and ESV index measured by free-breathing CMR were slightly higher (all P＜0.05), whereas the left ventricular ejection fraction and left ventricular mass were slightly lower (both P＜0.05). Nonetheless, the two methods demonstrated good agreement and correlation (r values: 0.85-0.99). Native T1 and T2 values in healthy subjects from free-breathing CMR were 1214.9±16.7ms and 38.4±3.2ms, respectively. Among the 211 patients, 147 were LGE positive. Except for five patients with image quality scores below 3, all others had scores of 3 or higher.

conclusionFull free-breathing CMR examinations are feasible and effective in clinical practice, significantly reduce scan time while maintaining high image quality.

Indexed as

Breath HoldingCardiovascular DiseasesMagnetic Resonance Imaging, CineRespirationAdolescentAdultAgedAged, 80 and overChildFeasibility StudiesFemaleHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesCardiac magnetic resonanceCineFree-breathingLate gadolinium enhancementMotion correction

Identifiers

PMID40921253
PMCPMC12730850

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.