Evidence map›Paper›PMID 40921178›Full record

ArticleJournal of the American Chemical Society2025

Structural Basis for 3-Amino-3-carboxypropyl Transfer in Nocardicin Biosynthesis.

Yaojie Gao, Masayuki Karasawa, Zhiyang Quan, Takahiro Mori, Masahiro Kanaida, Craig A Townsend, Tohru Terada, Ikuro Abe, Takayoshi Awakawa

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yaojie GaoGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.
Masayuki KarasawaGraduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Zhiyang QuanRiken, Center for Sustainable Resource Sciences, Saitama 351-0198, Japan.
Takahiro MoriGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.ORCID 0000-0002-2754-5858
Masahiro KanaidaGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.
Craig A TownsendDepartment of Chemistry, Johns Hopkins University, Baltimore 21218, United States.ORCID 0000-0003-2795-7585
Tohru TeradaGraduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0000-0002-7091-0646
Ikuro AbeGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.ORCID 0000-0002-3640-888X
Takayoshi AwakawaRiken, Center for Sustainable Resource Sciences, Saitama 351-0198, Japan.ORCID 0000-0003-2575-3175

Funding

Biosynthesis of Beta Lactam AntibioticsR01AI121072 · NIAID · JOHNS HOPKINS UNIVERSITY · PI TOWNSEND, CRAIG ARTHUR · 2016 to 2025
$4.9M
B LACTAM AND AMINO ACID DERIVED ANTIBIOTIC BIOSYNTHESISR01AI014937 · NIAID · JOHNS HOPKINS UNIVERSITY · PI TOWNSEND, CRAIG A · 1985 to 2003
$1.5M
NIAID NIH HHS R01 AI014937NIAID NIH HHS R01 AI121072
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LactamsS-AdenosylmethionineCrystallography, X-RayModels, MolecularMolecular Dynamics SimulationLactamsnocardicinS-Adenosylmethionine

Identifiers

PMID40921178
PMCPMC12985355

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.