ArticleJournal of neurosurgery. Case lessons2025
CPPD-related basilar impression with vertebral artery dissection and subsequent subarachnoid hemorrhage: illustrative case.
Article in Journal of neurosurgery. Case lessons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCalcium pyrophosphate dihydrate (CPPD) deposition disease at the craniocervical junction (CCJ) typically presents with a retro-odontoid pseudotumor. Here, the authors report a case of CPPD-induced basilar impression, causing vertebral artery (VA) dissection and hemorrhage. OBSERVATIONS: A 65-year-old male presented with worsening chronic cervicalgia, occipital headaches, and unstable tandem gait. CT revealed basilar impression with severe atlantoaxial erosion and instability, absent on imaging 8 months prior. MRI showed high-grade CCJ stenosis without myelopathy, due to CPPD. Before treatment could be initiated, the patient was suddenly found unresponsive. CT showed posterior fossa hemorrhage due to VA dissection, with secondary obstructive hydrocephalus. An external ventricular drain was placed, followed by coil VA embolization. After halo vest placement, CCJ alignment was restored and the patient underwent occipitocervical fusion. Following prolonged rehabilitation, he regained independent living without significant neurological sequelae. LESSONS: This is the first reported case of VA dissection with posterior fossa hemorrhage secondary to basilar impression due to CPPD. Inflammatory arthritides of the CCJ may cause rapidly progressive atlantoaxial erosion, predisposing one to unstable basilar impression and VA dissection. Awareness of this risk is crucial in the surgical management of inflammatory basilar impression, where preoperative vascular imaging may be warranted in selected cases. https://thejns.org/doi/10.3171/CASE25332.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.