Evidence map›Paper›PMID 40920914›Full record

Trial reportAmerican journal of respiratory and critical care medicine2025

Randomized Sham-controlled Trial of Targeted Lung Denervation in Patients with Chronic Obstructive Pulmonary Disease (AIRFLOW-3).

Pallav L Shah, Dirk-Jan Slebos, Richard Sue, Surya P Bhatt, Christian Ghattas, Charlie Strange, Bruno Degano, Arschang Valipour, Stephan Eisenmann, Jose De Cardenas and 11 more

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Pallav L ShahRoyal Brompton & Harefield National Health Service Trust, Chelsea & Westminster Hospital and Imperial College, London, United Kingdom.ORCID 0000-0002-9052-4638
Dirk-Jan SlebosDepartment of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Richard SueHonor Health Medical Center, Phoenix, Arizona.
Surya P BhattDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-8418-4497
Christian GhattasThe Ohio State University Wexner Medical Center, Columbus, Ohio.
Charlie StrangeMedical University of South Carolina, Charleston, South Carolina.
Bruno DeganoHôpital Universitaire Rhône-Alpes, Grenoble, France.ORCID 0000-0003-1644-7264
Arschang ValipourKarl-Landsteiner-Institute for Lung Research and Pulmonary Oncology, Klinik Floridsdorf, Vienna Health Care Group, Vienna, Austria.
Stephan EisenmannUniversity Hospital Halle, Halle, Germany.
Jose De CardenasUniversity of Michigan Medical School, Ann Arbor, Michigan.
Charles-Hugo MarquetteCentre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Institute for Research on Cancer and Aging Nice Team 3, Université Côte d'Azur, Centre Hospitalier Universitaire de Nice, Fédération Hospitalo-Universitaire OncoAge, Nice, France.ORCID 0000-0002-0846-9941
Jose Soto-SotoAscension St. Vincent's Southside Hospital, Jacksonville, Florida.
Frank C SciurbaUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Francesca ConwayRoyal Brompton & Harefield National Health Service Trust, Chelsea & Westminster Hospital and Imperial College, London, United Kingdom.
James TonkinRoyal Brompton & Harefield National Health Service Trust, Chelsea & Westminster Hospital and Imperial College, London, United Kingdom.
Anand TanaRoyal Brompton & Harefield National Health Service Trust, Chelsea & Westminster Hospital and Imperial College, London, United Kingdom.
Nathaniel MarchettiLewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Jorine E HartmanDepartment of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0001-8765-9673
Valentin HeluainLarrey University Hospital, Toulouse, France; and.
Nicolas GuibertLarrey University Hospital, Toulouse, France; and.ORCID 0000-0001-9082-3008
Gerard J CrinerLewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.ORCID 0000-0003-1267-3483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DenervationLungPulmonary Disease, Chronic ObstructiveAgedDisease ProgressionDouble-Blind MethodFemaleForced Expiratory VolumeHumansMaleMiddle AgedQuality of LifeTreatment OutcomeacetylcholineanticholinergicbronchoscopyCOPDtargeted lung denervation

Identifiers

PMID40920914
PMCPMC12700255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.