Evidence map›Paper›PMID 40920896›Full record

Observational studyAnnals of the American Thoracic Society2025

Neutrophil-to-Lymphocyte Ratio as a Biomarker in Clinically Stable Chronic Obstructive Pulmonary Disease: SPIROMICS Cohort.

Daniel T Hoesterey, Hong Dang, Daniela Markovic, Russell G Buhr, Donald P Tashkin, R Graham Barr, John A Belperio, Russell P Bowler, Eugene R Bleecker, David J Couper and 25 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Annals of the American Thoracic Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors.

Daniel T HoestereyUniversity of Washington, Seattle, Washington.ORCID 0000-0001-9834-4896
Hong DangUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Daniela MarkovicUniversity of California, Los Angeles, Los Angeles, California.
Russell G BuhrUniversity of California, Los Angeles, Los Angeles, California.ORCID 0000-0001-6159-7435
Donald P TashkinUniversity of California, Los Angeles, Los Angeles, California.
R Graham BarrColumbia University Medical Center, New York, New York.
John A BelperioUniversity of California, Los Angeles, Los Angeles, California.
Russell P BowlerCleveland Clinic, Cleveland, Ohio.ORCID 0000-0003-4651-363X
Eugene R BleeckerUniversity of Arizona, Tucson, Arizona.
David J CouperUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Gerard J CrinerTemple University Hospital, Philadelphia, Pennsylvania.
Christopher B CooperUniversity of California, Los Angeles, Los Angeles, California.
Claire M DoerschukUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0003-2638-3321
Mark T DransfieldUniversity of Alabama at Birmingham, Birmingham, Alabama.
M Bradley DrummondUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-6968-4610
Ashraf FawzyJohns Hopkins University, Baltimore, Maryland.
Christine M FreemanUniversity of Michigan, Ann Arbor, Michigan.
MeiLan K HanUniversity of Michigan, Ann Arbor, Michigan.
Nadia N HanselJohns Hopkins University, Baltimore, Maryland.
Annette T HastieWake Forest School of Medicine, Winston-Salem, North Carolina.ORCID 0000-0001-6607-7797
Eric A HoffmanUniversity of Iowa Carver College of Medicine, Iowa City, Iowa.ORCID 0000-0001-8456-9437
Yvonne J HuangUniversity of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-7497-6597
Robert J KanerWeill Cornell Medical College, New York, New York.
Richard E KannerUniversity of Utah Spencer Fox Eccles School of Medicine, Salt Lake City, Utah.
Victor KimTemple University Hospital, Philadelphia, Pennsylvania.
Jerry A KrishnanUniversity of Illinois Chicago, Chicago, Illinois.ORCID 0000-0001-5525-4778
Fernando J MartinezWeill Cornell Medical College, New York, New York.
Wanda K O'NealUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Victor E OrtegaMayo Clinic, Phoenix, Arizona; and.
Robert PaineUniversity of Utah Spencer Fox Eccles School of Medicine, Salt Lake City, Utah.
Abhishek K ShrivastavMayo Clinic, Phoenix, Arizona; and.
J Michael WellsUniversity of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0001-9612-5454
Prescott G WoodruffUniversity of California, San Francisco, San Francisco, California.
Jeffrey L CurtisUniversity of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-5191-4847
Igor BarjaktarevicUniversity of California, Los Angeles, Los Angeles, California.

Funding

COPD FoundationFoundation for the NIHNHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS L30 HL134025NIH
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LymphocytesNeutrophilsPulmonary Disease, Chronic ObstructiveSmokingAgedBiomarkersCross-Sectional StudiesDisease ProgressionFemaleForced Expiratory VolumeHumansLeukocyte CountLymphocyte CountMaleMiddle AgedPrognosisBiomarkerschronic obstructive pulmonary diseasecigarette smokinginflammationmortalityneutrophils

Identifiers

PMID40920896
PMCPMC12700239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.