ArticlePloS one2025
"Colorectal Cancer Care Quality in a Developing Country: Insights from a Comparison of Teaching and Non-teaching Hospitals in Iran".
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur study represents the first effort in the Eastern Mediterranean Region to identify disparities in the quality of colorectal cancer (CRC) care in Iran.
methodsWe established a collaborative registry program for non-metastatic CRC patients to evaluate survival rates between teaching cancer centers (TCCs) and a high-volume, non-teaching, non-cancer center (NTNC). The study included a diverse patient population and considered various factors such as cancer stage, margin involvement, adherence to guidelines for adjuvant and neoadjuvant treatments, emergency surgeries, socioeconomic status, and risk of surgery. We utilized a multivariate Cox regression model and the targeted maximum likelihood estimator (TMLE) to analyze survival disparities in colorectal cancer between TCCs and the NTNC.
resultsWe recruited 668 CRC patients, including 320 with colon cancer and 298 with rectal cancer. Patients who underwent surgery at teaching cancer centers (TCCs) displayed significantly higher quality of care and better outcomes than those treated at the non-teaching, non-cancer center (NTNC). The adjusted hazard ratios (HR) were 1.97 (95% CI 1.21-3.21) for colon cancer and 1.54 (95% CI 1.01-2.55) for rectal cancer. Additionally, we observed significant causal mortality risk ratios (RR) based on hospital type for overall colorectal cancer (RR = 1.42, 95% CI 1.12-1.81) and specifically for colon (RR = 1.48, 95% CI 1.04-2.11) and rectum cancer (RR = 1.39, 95% CI 1.01-2.02).
conclusionThe survival disparities in colon and rectal cancers between TCCs and NTNCs highlight a significant gap in CRC care in Iran. It is essential to expand this study nationally and implement the knowledge and experiences from TCCs in other hospitals to improve the quality of care and enhance patient outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.