Evidence map›Paper›PMID 40920662›Full record

ArticleACS macro letters2025

Introducing Disulfide Bonds into Polyester Biomaterials via Nucleophilic Thiol-yne Polymerization.

Daniele Giannantonio, Meltem Haktaniyan, Arianna Brandolese, Maria C Arno, Andrew P Dove

Abstract read
In one paragraph

Article in ACS macro letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniele GiannantonioSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.
Meltem HaktaniyanSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.ORCID 0000-0002-2185-1811
Arianna BrandoleseSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.
Maria C ArnoSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.ORCID 0000-0003-1734-4777
Andrew P DoveSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.ORCID 0000-0001-8208-9309

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyesters are a widely used class of biomaterials thanks to their (bio)degradability and tunable thermomechanical properties. Introducing dynamic disulfide bonds into their backbone enables them to be degraded through different routes and also imparts self-healing properties. However, while numerous polymerization protocols exist with which to introduce disulfide bonds into linear polymers, these methods lack the versatility needed to produce materials with diverse thermomechanical properties. In this work, nucleophilic thiol-yne polymerization was employed to synthesize polymers with a controllable amount of disulfide bonds in the backbone. The crystallinity and, hence, the thermomechanical properties of these polymers were tuned through the variation of different parameters such as disulfide bond content, polymer backbone conformational features (

Indexed as

Biocompatible MaterialsDisulfidesPolyestersSulfhydryl CompoundsHumansPolymerizationBiocompatible MaterialsDisulfidesPolyestersSulfhydryl Compounds

Identifiers

PMID40920662
PMCPMC12548359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.