Evidence map›Paper›PMID 40920241›Full record

ArticleArchives of gynecology and obstetrics2025

Misdiagnosis in patients with obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome: a retrospective study of 164 cases.

Shuang Song, Zhiyuan Dou, Jiali Tong, Yiwei Zhang, Lei Li, Na Chen, Lan Zhu

Abstract read
In one paragraph

Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuang SongDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan, Beijing, 100005, China.
Zhiyuan DouDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan, Beijing, 100005, China.
Jiali TongDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan, Beijing, 100005, China.
Yiwei ZhangDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan, Beijing, 100005, China.
Lei LiDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan, Beijing, 100005, China.
Na ChenDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan, Beijing, 100005, China.
Lan ZhuDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan, Beijing, 100005, China. zhu_julie@vip.sina.com.

Funding

National Key Clinical Specialty Construction Project U114000
6 · The paper itself

Abstract

purposeThe aim of this study was to summarize and analyze the incidence, underlying causes and related risk factors of misdiagnosis in patients with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA) syndrome.

methodsThis is a single center, retrospective study conducted in a tertiary hospital, enrolling patients diagnosed with OHVIRA syndrome in our center between January 2000 and December 2023, with intact charts retrieved. We collected information related to misdiagnosis. The main outcome was the incidence of misdiagnosis in OHVIRA patients. Misdiagnosis related information, including the primary diagnosis and following management were displayed. We also analyzed the potential risk factors of misdiagnosis in OHVIRA patients by logistic regression.

resultsAmong 164 cases enrolled, 27 (16.5%) patients had experienced misdiagnosis. The most frequent primary misdiagnoses were pelvic abscess (8/27, 29.6%) and ovarian cyst (7/27, 25.9%). Complicating with pelvic endometriosis was the potential risk factor of misdiagnosis (OR 3.267, 95% CI 1.010-10.660). Presenting with irregular bleeding (OR 0.193, 95%CI 0.047-0.800) and performing pelvic MRI prior to diagnosis (OR 0.157, 95% CI 0.050-0.486) were potential protective factors for misdiagnosis in patients with OHVIRA syndrome.

conclusionMisdiagnosis is not uncommon in patients with OHVIRA syndrome. Alerting to related symptoms and optimizing various imaging modalities can effectively reduce the risk of misdiagnosis.

Indexed as

Diagnostic ErrorsKidneyVaginaAdolescentAdultFemaleHumansMagnetic Resonance ImagingMiddle AgedRetrospective StudiesRisk FactorsSyndromeYoung AdultHerlyn-Werner-Wunderlich syndrome (HWWS)MisdiagnosisOHVIRA syndrome

Identifiers

PMID40920241
PMCPMC12589279

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.