Evidence map›Paper›PMID 40920228›Full record

ArticleInternational urogynecology journal2025

Complication Rates are Low for Women Aged 70 and Older Undergoing Sacrocolpopexy.

Tien C Nguyen, Halina Zyczynski, Mary F Ackenbom, Stephanie W Zuo

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Article in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Tien C NguyenUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Halina ZyczynskiDivision of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Mary F AckenbomDivision of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Stephanie W ZuoDivision of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. stephanie.zuo@uvahealth.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisAging may place patients at greater risk for adverse perioperative outcomes. We hypothesized that women undergoing minimally invasive (MIS) sacrocolpopexy aged ≥ 70 years are more likely to experience adverse events (AE) within 8 weeks of surgery.

methodsWe performed a secondary analysis of a retrospective study on perioperative adverse events in women ≥ 61 years old undergoing prolapse surgery at a single academic center from January 2016 to May 2023. Only women undergoing MIS sacrocolpopexy were included. The primary outcome was a composite 8-week AE outcome. Secondary outcomes included prolapse recurrence and mesh complication. Variables were compared between the groups using t-test (or Mann-Whitney U) and chi-square (or Fisher's exact) analyses. Multivariable logistic regression was performed, controlling for variables with p < 0.05 on univariate analysis.

resultsOf the 709 women who underwent MIS sacrocolpopexy, 29.9% (n = 212) were aged ≥ 70 years. Age ≥ 70 was not significantly associated with 8-week perioperative AEs, nor was it associated with prolapse recurrence or mesh complication. The composite AE outcome was not associated with age ≥ 70 on multivariable analysis, controlling for CCI score, robotic approach, and concomitant hysterectomy (adjusted odds ratio (aOR) 0.64, 95% confidence interval (CI) [0.38-1.10]). Women aged ≥ 70 years had a 73% lesser adjusted odds of surgical site infections on multivariable analysis (95% CI [0.08-0.93]).

conclusionsAge ≥ 70 years is not associated with perioperative AEs, prolapse recurrence, or mesh complication. These findings highlight the safety profile of this surgical approach in older women, an important consideration for urogynecologic surgeons caring for an aging population.

Indexed as

Gynecologic Surgical ProceduresPelvic Organ ProlapsePostoperative ComplicationsAgedAged, 80 and overAge FactorsFemaleHumansMiddle AgedMinimally Invasive Surgical ProceduresRecurrenceRetrospective StudiesSurgical MeshAdverse eventsAgingGeriatricsSacrocolpopexy

Identifiers

PMID40920228
PMCPMC12756190

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.