ArticleJournal of virology2025
Limiting viral replication in hematopoietic cells delays Rift Valley fever virus disease progression in C57BL/6 mice.
Lingqing Xu, Alden C Paine, Dominique J Barbeau, William Klimstra, Anita K McElroy
Abstract read
In one paragraphArticle in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
5 authors.
Lingqing XuDivision of Pediatric Infectious Disease, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-6451-1673 Alden C PaineDivision of Pediatric Infectious Disease, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Dominique J BarbeauDivision of Pediatric Infectious Disease, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6493-5022 William KlimstraCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Anita K McElroyDivision of Pediatric Infectious Disease, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6764-7536 Funding
Practices CoreUC7AI180311 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI William Paul Duprex · 2023 to 2026
$13.2MViral Persistence and PathogenesisT32AI049820 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DELUCA, NEAL A. · 2001 to 2024
$5.5MAn Informed Approach to Live Attenuated Vaccines against Encephalitis AlphavirusesR01AI153209 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLIMSTRA, WILLIAM B · 2020 to 2024
$2.9MInnate immune recognition and response to Rift Valley fever virusR01AI171200 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Anita K McElroy · 2022 to 2026
$2.2MNational Institute of Allergy and Infectious Diseases R01AI153209National Institute of Allergy and Infectious Diseases R01AI171200NIAID NIH HHS R01 AI153209NIAID NIH HHS R01 AI171200NIAID NIH HHS T32 AI049820NIAID NIH HHS UC7 AI180311
6 · The paper itselfAbstract
Rift Valley fever virus (RVFV) causes mild to severe disease in livestock and humans. It was first identified in 1931 during an epizootic in Kenya and has spread across Africa and into the Middle East. Hematopoietic cells are one of the major targets of RVFV
Indexed as
Hematopoietic Stem CellsMicroRNAsRift Valley FeverRift Valley fever virusVirus ReplicationAnimalsDisease ProgressionFemaleMiceMice, Inbred C57BLMicroRNAsMirn142 microRNA, mousehematopoietic cellsmicroRNARift Valley fever virustype I IFNviral pathogenesis
Identifiers
PMID40920082
PMCPMC12548454
What OpenQuestion holds
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LicenceCC BY
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