Evidence map›Paper›PMID 40920071›Full record

ArticlemSphere2025

Investigation of the global translational response to oxidative stress in the model archaeon

Emma Dallon, Haley M Moran, Sadhana R Chidambaran, Arman Kian, Betty Y H Huang, Stephen D Fried, Jocelyne DiRuggiero

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Emma DallonDepartment of Biology, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0009-0004-7325-2089
Haley M MoranDepartment of Chemistry, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0003-1845-3879
Sadhana R ChidambaranDepartment of Biology, Johns Hopkins University, Baltimore, Maryland, USA.
Arman KianDepartment of Biology, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0009-0000-3584-7461
Betty Y H HuangDepartment of Biology, Johns Hopkins University, Baltimore, Maryland, USA.
Stephen D FriedDepartment of Chemistry, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0003-2494-2193
Jocelyne DiRuggieroDepartment of Biology, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0001-6721-8061

Funding

The Chemistry-Biology Interface Program at Johns Hopkins UniversityT32GM080189 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ROKITA, STEVEN E · 2008 to 2022
$3.5M
Watching Proteins Fold (or Misfold) in vivo with Mass SpectrometryDP2GM140926 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI FRIED, STEPHEN DAVID · 2020 to 2020
$2.3M
The Chemistry-Biology Interface Program at Johns Hopkins UniversityT32GM149382 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI STEVEN E ROKITA · 2023 to 2026
$1.4M
National Science Foundation 2045844National Science Foundation MCB-2034271 and,MCB-57951NIGMS NIH HHS DP2 GM140926NIGMS NIH HHS DP2-GM140926NIGMS NIH HHS T32 GM080189NIGMS NIH HHS T32 GM149382
6 · The paper itself

Abstract

Oxidative stress induces a wide range of cellular damage, often causing disease and cell death. While many organisms are susceptible to the effects of oxidative stress, haloarchaea have adapted to be highly resistant. Several aspects of the haloarchaeal oxidative stress response have been characterized; however, little is known about the impacts of oxidative stress at the translation level. Using the model archaeon

Indexed as

Haloferax volcaniiOxidative StressProtein BiosynthesisRibosomesRNA, ArchaealRNA, Small UntranslatedGene Expression Regulation, ArchaealRNA, ArchaealRNA, Small Untranslatedarchaearibosome profilingsmall RNAsstress responsetranslational control

Identifiers

PMID40920071
PMCPMC12482152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.