Evidence map›Paper›PMID 40919898›Full record

ArticleJournal of virology2025

Influenza A virus circumvents the innate immune response through the sequestration of double-stranded RNA.

Masahiro Nakano, Sho Miyamoto, Chiho Ohnishi, Chiharu Nogami, Nanami Hirose, Yoko Fujita-Fujiharu, Yukiko Muramoto, Takeshi Noda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Masahiro NakanoLaboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.ORCID 0000-0003-4247-9008
Sho MiyamotoLaboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Chiho OhnishiLaboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Chiharu NogamiLaboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Nanami HiroseLaboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Yoko Fujita-FujiharuLaboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Yukiko MuramotoLaboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Takeshi NodaLaboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.ORCID 0000-0002-0658-4663

Funding

Japan Agency for Medical Research and Development 22KK0115, 24fk0108694h0001, 24fk0108694h0001Japan Science and Technology Agency JPMJCR20HAJapan Society for the Promotion of Science 16K08808, 19K07575Japan Society for the Promotion of Science JPJSCCA20190008, 22K19431
6 · The paper itself

Abstract

Double-stranded RNA (dsRNA), which induces an innate immune response against viral infections, is rarely detected in influenza A virus (IAV)-infected cells. Nevertheless, we previously reported that the influenza A viral ribonucleoprotein (vRNP) complex generates looped dsRNAs during RNA synthesis

Indexed as

Immune EvasionImmunity, InnateInfluenza A virusInfluenza, HumanRNA, Double-StrandedRNA, ViralA549 CellsAnimalsCell LineCell NucleusCytoplasmDogsHost-Pathogen InteractionsHumansInterferon Regulatory Factor-3Madin Darby Canine Kidney CellsINS1 protein, influenza virusInterferon Regulatory Factor-3RibonucleoproteinsRNA, Double-StrandedRNA, ViralViral Nonstructural Proteinsatomic force microscopydouble-stranded RNAimmunofluorescence assayinfluenza virusinnate immune evasion

Identifiers

PMID40919898
PMCPMC12548412

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.