Evidence map›Paper›PMID 40919816›Full record

ArticlemBio2025

Cwh8 moonlights as a farnesyl pyrophosphate phosphatase and is essential for farnesol biosynthesis in

Daniel J Gutzmann, Cory H T Boone, Brigid M Toomey, Shyanne Urbin, Wayne R Riekhof, Deborah A Hogan, Audrey L Atkin, Kenneth W Nickerson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel J GutzmannSchool of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID 0000-0001-5352-4826
Cory H T BooneSchool of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Brigid M ToomeySchool of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Shyanne UrbinSchool of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Wayne R RiekhofSchool of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Deborah A HoganDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-6366-2971
Audrey L Atkin *School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID 0000-0001-5893-1068
Kenneth W Nickerson *School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID 0000-0003-0310-6807

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
Acquisition of the NextSeq2000 Sequencing platform to Increase Next Generation Sequencing Throughput While Reducing Costs at DartmouthS10OD030242 · OD · DARTMOUTH COLLEGE · PI KOLLING IV, FRED W · 2021 to 2021
$321k
NCI NIH HHS P30 CA023108NIGMS NIH HHS 5P20GM103427NIGMS NIH HHS P20 GM103427NIH HHS S10 OD030242
6 · The paper itself

Abstract

In the opportunistic pathogen

Indexed as

Candida albicansFarnesolFungal ProteinsPhosphoric Monoester HydrolasesPolyisoprenyl PhosphatesGene Expression Regulation, FungalSesquiterpenesFarnesolfarnesyl pyrophosphateFungal ProteinsPhosphoric Monoester HydrolasesPolyisoprenyl PhosphatesSesquiterpenesCandida albicansfarnesol biosynthesis

Identifiers

PMID40919816
PMCPMC12505894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.