Evidence map›Paper›PMID 40919812›Full record

ArticlemBio2025

Probing the mechanism of peptidoglycan amidase activation by FtsEX-EnvC.

Jonathan Cook, Allister Crow

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jonathan CookSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.ORCID 0000-0003-3690-555X
Allister CrowSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.ORCID 0000-0001-6856-5962

Funding

Biotechnology and Biological Sciences Research Council BB/V017101/1
6 · The paper itself

Abstract

The FtsEX-EnvC-AmiA/B system is a key component of the

Indexed as

AmidohydrolasesBacterial ProteinsCell Cycle ProteinsEscherichia coliEscherichia coli ProteinsN-Acetylmuramoyl-L-alanine AmidaseCell DivisionEnzyme ActivationMutagenesis, Site-DirectedPeptidoglycanamidaseAmidohydrolasesBacterial ProteinsCell Cycle ProteinsEscherichia coli ProteinsFtsX protein, bacteriaN-Acetylmuramoyl-L-alanine AmidasePeptidoglycanbacterial cell divisionbacterial cell envelopecoiled coilsknobs-into-holes packingpeptidoglycan amidasestructural microbiologytype VII ABC transporters

Identifiers

PMID40919812
PMCPMC12505981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.