ArticleMicrobiology spectrum2025
Effect of guideline-concordant, appropriate, and effective antimicrobial treatment on patient outcome in multidrug-resistant (MDR) infections.
Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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9 authors.
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Abstract
Recently, to achieve cure, physicians have been resorting to overuse or misuse of antimicrobials to treat resistant infections, leading to the emergence of further resistant organisms. To overcome this issue, antimicrobial guidelines have been developed. Nevertheless, recently, controversy regarding the effect of adherence to antimicrobial guidelines on patient outcomes has been raised. Additionally, in multidrug-resistant (MDR) infections, rates of susceptibility to guideline-recommended agents have been reported to be low. Hence, herein, we aim to assess the impact of guideline-concordant, appropriate, and effective antimicrobial regimens on patient outcomes in MDR infections at the Ministry of National Guard Health Affairs (MNGHA), Jeddah, Saudi Arabia. This retrospective cross-sectional study was conducted at MNGHA, a 500-bed tertiary care hospital in Jeddah, Saudi Arabia. Saved microbiology lab samples that grew ESKAPE pathogens (
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