Evidence map›Paper›PMID 40919703›Full record

ArticleJournal of agricultural and food chemistry2025

Mapping Royal Jelly's Bioactive Profile by Liquid Chromatography Coupled to Trapped Ion Mobility Spectrometry and High-Resolution Mass Spectrometry.

Eleni S Nastou, Dafni A Preza-Mayo-Kataki, Panagiotis-Loukas P Gialouris, Niki C Maragou, Evagelos E Gikas, Nikolaos S Thomaidis

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eleni S NastouLaboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, Athens 15771, Greece.ORCID 0009-0003-3919-288X
Dafni A Preza-Mayo-KatakiLaboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, Athens 15771, Greece.ORCID 0009-0005-6682-5958
Panagiotis-Loukas P GialourisLaboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, Athens 15771, Greece.ORCID 0009-0009-2040-2780
Niki C MaragouLaboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, Athens 15771, Greece.ORCID 0000-0002-2464-5108
Evagelos E GikasLaboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, Athens 15771, Greece.ORCID 0000-0002-0107-9991
Nikolaos S ThomaidisLaboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, Athens 15771, Greece.ORCID 0000-0002-4624-4735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An innovative 4D targeted method was developed for the determination of 61 bioactive compounds in royal jelly (RJ) related to their health-promoting properties. The method, apart from high-resolution mass spectrometry, exploits the advantages of vacuum-insulated probe-heated electrospray ionization source (VIP-HESI), reducing thermal degradation, and trapped ion mobility spectrometry (TIMS), improving selectivity and compound identification. The optimization of VIP-HESI ionization parameters using experimental designs showed that the critical parameters were the capillary voltage as well as the probe gas flow rate and temperature. The LODs of the validated method ranged between 0.0013 and 0.090 μg g

Indexed as

Fatty AcidsIon Mobility SpectrometryMass SpectrometrySpectrometry, Mass, Electrospray IonizationChromatography, High Pressure LiquidRoyal JellyFatty AcidsRoyal Jelly4-hydroxybenzaldehydebee productsHRMSmethod validationpinocembrinpolyphenols

Identifiers

PMID40919703
PMCPMC12447487

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.