Evidence map›Paper›PMID 40919671›Full record

SynthesisClinical and experimental dental research2025

The Impact of Mini-Screws and Micro-Implants on Orthodontic Clinical Outcomes: An Umbrella Meta-Analysis.

Abdolreza Jamilian, Helen Jamloo, Kurosh Majidi, Meysam Zarezadeh

Abstract readMeta-Analysis
In one paragraph

Synthesis in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdolreza JamilianThe City of London Dental School, University of Greater Manchester, Bolton, UK.ORCID 0000-0002-8841-0447
Helen JamlooSchool of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Kurosh MajidiDepartment of Orthodontics, Smile Tailor Private Practice, London, UK.
Meysam ZarezadehDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Funding

The authors received no specific funding for this study.
6 · The paper itself

Abstract

objectivesThis umbrella meta-analysis aimed to answer the clinical question: Do mini-screws and micro-implants improve specific orthodontic outcomes such as intermolar width, interpremolar width, suture expansion, molar movement, and skeletal width compared to conventional anchorage methods? MATERIALS AND

methodsA systematic search was performed in PubMed, Scopus, ISI Web of Science, and Google Scholar up to October 2024. Systematic reviews and meta-analyses on mini-screws and micro-implants in orthodontic treatment were included. Methodological quality was assessed using AMSTAR 2, and a random-effects model was used to calculate effect sizes (ESs) and 95% confidence intervals (CIs). Heterogeneity was evaluated using the I² statistic and Cochrane's Q-test, with subgroup and sensitivity analyses conducted to identify sources of heterogeneity.

resultsEleven meta-analyses comprising 50 data sets were included. The results indicated that mini-screws significantly increased intermolar width (ES: 2.61 mm, 95% CI: 0.29-4.92, p = 0.02) and skeletal width (ES: 3.33 mm, 95% CI: 1.37-5.29, p = 0.001). However, no significant impact was found on interpremolar width or alveolar width before and after MARPE. Micro-implants significantly reduced molar movement (ES: -1.13 mm, 95% CI: -1.99 to -0.26, p = 0.01). Substantial heterogeneity was noted across several outcomes (I² > 50%), which persisted despite subgroup analyses.

conclusionMini-screws and micro-implants enhance skeletal and intermolar width and control molar movement in orthodontic treatment. However, their effects on other outcomes are inconsistent, warranting further high-quality studies to strengthen clinical recommendations.

trial registrationPROSPERRO (CRD42023447137).

Indexed as

Bone ScrewsDental ImplantsOrthodontic Anchorage ProceduresTooth Movement TechniquesHumansMeta-Analysis as TopicSystematic Reviews as TopicTreatment OutcomeDental Implantsmicro‐implantsmini‐screwsorthodonticsumbrella meta‐analysis

Identifiers

PMID40919671
PMCPMC12415713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.