Trial reportClinical and experimental dental research2025
Effect of Ozonated Water in Nonsurgical Management of Periodontitis.
Trial report in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effect of Ozonated Water in Nonsurgical Management of Periodontitis.Clinical and experimental dental research · 2025Trial
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectivesDue to ozonated water's antimicrobial and anti-inflammatory properties, it may be used as a supplementary treatment to scaling and root planing (SRP). The present study aimed to evaluate the clinical effectiveness of using ozonated water instead of tap water during the SRP for people with chronic generalized periodontitis. MATERIAL AND
methodsThis randomized clinical trial was conducted on 30 patients with generalized periodontitis Stages I and II, randomly allocated to two groups. Test sites were subjected to ozonated water, and control sites were subjected to tap water. The clinical periodontal parameters were measured at baseline, the 4th, and 8th week of treatment.
resultsFindings showed a significant decrease in periodontal pocket depth (PPD), clinical attachment level (CAL), and gingival index (GI) at both the 4th and the 8th week of treatment in both groups. PPD was further reduced in the test group, but the difference between the two groups was not significant. However, the greater reduction of CAL at the 4th and 8th week (p < 0.001 and p < 0.001, respectively) and also the greater reduction of GI at the 4th week (p = 0.01) was observed in the test group.
conclusionsBoth the test and control groups showed clinical improvement following nonsurgical periodontal therapy. The ozonated water group demonstrated significantly greater reductions in CAL at the 4th and 8th weeks, and in GI at the 4th week. However, the magnitude of these differences was modest and may have limited clinical relevance. Further research is needed to confirm long-term outcomes.
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