ArticleJournal of experimental orthopaedics2025
An evaluation of a low-cost platelet-rich plasma for osteoarthritis of the knee: A pilot study.
Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07231471 (Platelet Rich Plasma for Musculoskeletal Conditions), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Platelet Rich Plasma for Musculoskeletal Conditions
Who cites it
1 citing paper in PubMed.
- An evaluation of a low-cost platelet-rich plasma for osteoarthritis of the knee: A pilot study.Journal of experimental orthopaedics · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Purpose: To assess the characteristics and effectiveness of low-cost platelet-rich plasma (LC-PRP) for knee osteoarthritis (OA) by evaluating its composition and effect on pain, function, satisfaction, safety and cost-effectiveness. Methods: Level IV evidence single-arm prospective cohort pilot study of 20 subjects (30 knees total) with mild-to-moderate knee OA. Two LC-PRP injections were performed, 3 weeks apart. Platelet extraction/yield, patient-reported outcomes and incidence of adverse events were assessed with a primary endpoint of 6 months. A cost-effectiveness analysis of LC-PRP compared to corticosteroid injection was conducted. Results: On average, this LC-PRP preparation method allowed for recovery of 85% of platelets. Significant mean differences in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores (total, pain and function) and global assessment score were observed at all follow-up points compared to baseline ( Conclusions: This pilot study demonstrates that LC-PRP ($11) may significantly benefit patients with knee OA. LC-PRP appears to be a safe, cost-effective means for improving pain and function in knee OA. Level of Evidence: Level IV.
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Registered trials
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