Evidence map›Paper›PMID 40919434›Full record

ArticleFrontiers in genetics2025

Comparative genomic insights into adaptation, selection signatures, and population dynamics in indigenous Indian sheep and foreign breeds.

Malarmathi Muthusamy, Oludayo Michael Akinsola, Pritam Pal, Chitra Ramasamy, Saravanan Ramasamy, Abdulraheem Arome Musa, Aranganoor Kannan Thiruvenkadan

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Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Malarmathi MuthusamyDepartment of Animal Genetics and Breeding, Veterinary College and Research Institute, TANUVAS, Namakkal, India.
Oludayo Michael AkinsolaDepartment of Animal Genetics and Breeding, Veterinary College and Research Institute, TANUVAS, Namakkal, India.
Pritam PalAnimal Genetics and Breeding Division, Indian Council of Agricultural Research (ICAR)-National Dairy Research Institute (NDRI), Karnal, India.
Chitra RamasamyDepartment of Animal Genetics and Breeding, Veterinary College and Research Institute, TANUVAS, Namakkal, India.
Saravanan RamasamyDepartment of Animal Genetics and Breeding, Veterinary College and Research Institute, TANUVAS, Namakkal, India.
Abdulraheem Arome MusaResearch Institute for Farm Animal Biology (FBN), Dummerstorf, Germany.
Aranganoor Kannan ThiruvenkadanCollege of Poultry Production and Management, TANUVAS, Hosur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: India's indigenous sheep breeds have evolved under extreme and diverse agro-ecological pressures, yet the genomic basis of their resilience and local adaptation remains poorly understood. Method: This study combines genomic inbreeding estimates, runs of homozygosity (ROH), population structure analyses, and composite selection scans to investigate three native Indian breeds-Changthangi, Deccani, and Garole-within a panel of nine breeds that also includes populations from Africa (Ethiopian Menz), East and South Asia (Tibetan, Chinese Merino, Bangladesh Garole, Bangladesh East), and Europe (Suffolk). Results: ROH and heterozygosity estimates revealed strong contrasts: Bangladesh East sheep exhibited high genomic inbreeding (F Conclusion: These findings reveal ecotype-pecific adaptive nature shaped by polygenic selection, gene flow, and demography, offering actionable insights for sustainable smallholder breeding strategies.

Indexed as

effective population sizegenomic inbreedingindigenous sheeplivestock conservation geneticspolygenic adaptationpopulation structureruns of homozygosity (ROH)selection signatures

Identifiers

PMID40919434
PMCPMC12408274

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