Evidence map›Paper›PMID 40919417›Full record

ArticleJournal of Alzheimer's disease reports

Apolipoprotein E4 allele, antibodies against periodontal microorganisms, and cognition in older adults.

Anwar T Merchant, Longgang Zhao, Eric Mishio Bawa, Amirhossein Fakhre Yaseri, Matthew Lohman, Jiajia Zhang, Alyssa Clay-Gilmour, Roger D Newman-Norlund, Julius Fridriksson

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anwar T MerchantDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.ORCID https://orcid.org/0000-0003-1045-5079
Longgang ZhaoDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Eric Mishio BawaDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Amirhossein Fakhre YaseriDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Matthew LohmanDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Jiajia ZhangDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Alyssa Clay-GilmourDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Roger D Newman-NorlundCommunication Sciences and Disorders, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Julius FridrikssonCommunication Sciences and Disorders, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The presence of the apolipoprotein E4 ( Objective: To assess whether the presence of the Methods: This cross-sectional analysis was conducted among participants of the third National Health and Nutrition Examination Survey (NHANES III) (1988 to 1994), aged 60 years and older, with measurements of IgG antibodies against 19 periodontal microorganisms and Results: Approximately 77.5% of participants carried no Conclusions: Mean cognitive scores were lower among

Indexed as

Alzheimer's diseaseAPOE4cognitionIgG antibodiesoral healthoral microorganismsperiodontal disease

Identifiers

PMID40919417
PMCPMC12413519

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.