ReviewReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2025
Pseudogenes in the carcinogenesis: epithelial-to-mesenchymal transition process and cancer initiating cells.
Review in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Initially, pseudogenes were considered to be "junk DNA", and their biological role was unclear. However, some of the pseudogenes are engaged in the process of cancerogenesis and perform essential functions in competing for endogenous ribonucleic acid (ceRNA) networks and competing for RNA binding proteins (RBPs). They either positively or negatively regulate gene expression and act as suppressive and oncogenic transcripts. In this review, we look at some of the pseudogenes that play a role in the epithelial-to-mesenchymal transition (EMT) process and the maintenance of cancer-initiating cells (CIC), which are essential in understanding cancer development and progression metastasis and resistance to commonly used therapies. The group of discussed pseudogenes consists of
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