ArticleFrontiers in microbiology2025
Maternal β-carotene addition has long-term effects on intestinal health of offspring chicks.
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- The Impact of Oral-Gut Microbiota Structure and Its Manipulation on RA Development and Management.Food science & nutrition · 2026Review
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6 authors.
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Abstract
Background: Maternal dietary intervention utilizing complex additives rich in β-carotene has demonstrated the capacity to enhance embryonic intestinal development and influence microbial composition in offspring. Nevertheless, the extended impact of maternal β-carotene inclusion on the intestinal health of post-hatching chicks is still not fully elucidated. Objective: This research aimed to evaluate the impacts of maternal β-carotene supplementation on the intestinal development and microbial communities in chicks after hatching. Methods: A total of 1,215 Hy-Line Brown laying hens were divided into three groups, with each group containing five subgroups of 81 hens each. The hens received a basal diet (CON) or diets added with β-carotene at 120 mg/kg (LBC) or 240 mg/kg (HBC). After 6 weeks of dietary intervention, eggs were collected for incubation. Following hatching, 40 male chicks from each group were randomly chosen and evenly distributed into five distinct subgroups. All chicks were then reared on a uniform basal diet for a duration of 6 weeks. Results: Chicks from the LBC group exhibited significantly higher initial body weight, enhanced villus height (VH), greater villus height to crypt depth ratio (VCR), higher goblet cell (GC) density, and elevated expression of Mucin 2 ( Conclusion: These findings suggest that maternal β-carotene addition confers sustained benefits to intestinal health in offspring, potentially mediated by modulation of the cecal microbiome up to day 42.
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