Evidence map›Paper›PMID 40919174›Full record

ArticleUrology case reports2025

Spinal cord compression as the initial presentation of de novo metastatic testicular seminoma: A rare and complex case.

Jordan Santucci, Peter Stapleton, Jack West, Siyu Huang, Nathan Lawrentschuk, Stephen Brown, Robert Forsyth, Niranjan Sathianathen

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PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jordan SantucciGrampians Health, Ballarat, VIC, Australia.
Peter StapletonGrampians Health, Ballarat, VIC, Australia.
Jack WestGrampians Health, Ballarat, VIC, Australia.
Siyu HuangGrampians Health, Ballarat, VIC, Australia.
Nathan LawrentschukRoyal Melbourne Hospital, Parkville, VIC, Australia.
Stephen BrownGrampians Health, Ballarat, VIC, Australia.
Robert ForsythGrampians Health, Ballarat, VIC, Australia.
Niranjan SathianathenAustin Health, Heidelberg, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a 43-year-old man with de novo metastatic testicular seminoma complicated by paraplegia from spinal cord compression due to retroperitoneal lymphadenopathy. Urgent retroperitoneal biopsy confirmed seminoma and, after the patient declined neurosurgical intervention, systemic chemotherapy was promptly initiated prior to delayed orchidectomy. Post-chemotherapy orchidectomy histology revealed minimal viable tumour and serial imaging showed a residual retroperitoneal mass with low-grade uptake on FDG-PET. The mass was deemed unresectable, and surveillance was favoured over immediate salvage. This case highlights the importance of timely diagnosis, multidisciplinary care, and guideline-informed flexibility in managing advanced seminoma with rare complications such as spinal cord compression.

Indexed as

BEP chemotherapyFDG-PETMetastatic seminomaResidual retroperitoneal massSpinal cord compressionTesticular cancer

Identifiers

PMID40919174
PMCPMC12410193

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.