ArticleUrology case reports2025
Metastatic cardiac tumor resulting in cardiogenic shock from muscle-invasive urothelial carcinoma of the bladder: a case report.
Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Muscle-invasive bladder cancer (MIBC) with cardiac metastasis typically carries a very poor prognosis. A Black woman in her 70s developed high-grade urothelial carcinoma with squamous differentiation invading the bladder muscle. Despite chemotherapy, radiation, and nephrostomy, the disease progressed. Six months after diagnosis, imaging revealed metastases to the heart and liver with biopsy showing a rare p63-positive, CK7-negative phenotype. Following a single dose of pembrolizumab, she died within three weeks, likely from cardiogenic shock. In CK7-negative variant urothelial carcinoma, early cardiac imaging and expanded immunohistochemical panels may improve detection of atypical metastases.
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