Evidence map›Paper›PMID 40919037›Full record

ArticleFrontiers in veterinary science2025

Optimizing equine standing sedation:

Julia de Assis Arantes, Isabela Peixoto Rabelo, Lucas Bermudes, Milena Domingues Lacerenza, Rubens Peres Mendes, Rodrigo Romero Corrêa, Diego Iwao Yamada, Carlos Augusto de Araújo Valadão, Renata Gebara Sampaio Dória

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julia de Assis Arantes *Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering (FZEA), University of Sao Paulo (USP), Pirassununga, SP, Brazil.
Isabela Peixoto Rabelo *Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering (FZEA), University of Sao Paulo (USP), Pirassununga, SP, Brazil.
Lucas Bermudes *Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering (FZEA), University of Sao Paulo (USP), Pirassununga, SP, Brazil.
Milena Domingues Lacerenza *Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering (FZEA), University of Sao Paulo (USP), Pirassununga, SP, Brazil.
Rubens Peres Mendes *Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering (FZEA), University of Sao Paulo (USP), Pirassununga, SP, Brazil.
Rodrigo Romero CorrêaDepartment of Surgery, School of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP), São Paulo, SP, Brazil.
Diego Iwao YamadaDepartment of Veterinary Medicine and Surgery, Faculty of Agricultural and Veterinary Sciences (UNESP), São Paulo State University, Jaboticabal, São Paulo, Brazil.
Carlos Augusto de Araújo ValadãoDepartment of Veterinary Medicine and Surgery, Faculty of Agricultural and Veterinary Sciences (UNESP), São Paulo State University, Jaboticabal, São Paulo, Brazil.
Renata Gebara Sampaio DóriaDepartment of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering (FZEA), University of Sao Paulo (USP), Pirassununga, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to compare the sedation quality and cardiorespiratory and behavioral effects of detomidine administered intravenously, either in intermittent boluses or as a continuous rate infusion, with butorphanol in horses pre-medicated with acepromazine for odontoplasty procedures. Methods: A prospective clinical study was conducted with fifteen adult horses randomly assigned to two groups: Bolus group (BG, Results: Continuous infusion of detomidine resulted in superior sedation quality, greater stability, and a reduced need for rescue sedation ( Conclusions and clinical relevance: Continuous infusion of detomidine with butorphanol provided more stable sedation, reducing the need for frequent redosing, but also led to prolonged ataxia. Future studies should explore alternative drug combinations to optimize sedation quality while minimizing ataxia and cardiorespiratory effects.

Indexed as

anesthetic managementclinical monitoringequine dentistryinfusion techniquessedation protocols

Identifiers

PMID40919037
PMCPMC12410164

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.