Evidence map›Paper›PMID 40918913›Full record

ArticleCureus2025

Management of Muscle-Invasive Bladder Urothelial Carcinoma in a South Asian Adult Man: Utility of Adaptive Radiotherapy in a Resource-Limited Country.

Sadia Sadiq, Arham Amir Khawaja, Haseeb Mehmood Qadri

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sadia SadiqRadiation Oncology, Institute of Nuclear Medicine and Oncology (INMOL) Atomic Energy Cancer Hospital, Lahore, PAK.
Arham Amir KhawajaGeneral Surgery and Surgical Oncology, Shaikh Zayed Medical Complex, Lahore, PAK.
Haseeb Mehmood QadriGeneral Surgery, Lahore General Hospital, Lahore, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary bladder cancer contributes significantly to the global cancer burden and is more prevalent in the developed world. We present the case of a 54-year-old male smoker who underwent transurethral resection of bladder tumor and consequent trimodality therapy (induction chemotherapy followed by concomitant chemo-radiotherapy). His disease was staged at cT3N0M0. Cone beam computed tomography (CBCT) and plan-of-the-day adaptive radiotherapy (ART) were utilized to treat muscle-invasive bladder urothelial carcinoma (MIBC). Instead of the usual planning treatment volume (PTV) of 2 cm, the disease-free state was achieved with a small PTV of 5 mm in 18 fractions and a large PTV of 1.5 cm in two fractions only. The volume of bowel saved with this strategy was 180 cc. The patient tolerated the treatment well with no side effects and is living a healthy life till date. CBCT-guided ART with plan-of-the-day approach is a precise and effective approach for the management of MIBC within limited resources.

Indexed as

adaptive radiotherapybladder cancerlimited resourceslow- to middle-income countriesoncologypakistanplanned treatment volumeurinary bladder

Identifiers

PMID40918913
PMCPMC12413917

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.