Evidence map›Paper›PMID 40918880›Full record

ArticleCureus2025

Effectiveness and Safety of Risankizumab for Psoriasis in a Liver Transplant Patient With Recurrent Metastatic Hepatocellular Carcinoma.

Sandy Sylvain, Christine Silvain, Matthieu Bainaud, Thomas Kerforne, Marie Masson Regnault

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. IL-23 Inhibitors in Psoriasis: What Have We Learnt so Far?Journal of inflammation research · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandy SylvainDermatology, Poitiers University Hospital, Poitiers, FRA.
Christine SilvainGastroenterology, Poitiers University Hospital, Poitiers, FRA.
Matthieu BainaudOncology, Poitiers University Hospital, Poitiers, FRA.
Thomas KerforneOrgan and Tissue Procurement Coordination, Poitiers University Hospital, Poitiers, FRA.
Marie Masson RegnaultDermatology, Hôpital Privé Francheville, Perigueux, FRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Risankizumab (RZB) is a humanized monoclonal antibody that selectively targets interleukin-23 (IL-23). It has proven particularly effective in treating psoriasis, a common chronic inflammatory skin disease. However, its use remains poorly documented in certain populations, including patients with a history of solid organ transplantation or recent/active malignancy. We present a case of successful and well-tolerated treatment with RZB over an 18-month follow-up period in a patient with multiple comorbidities, including liver transplantation, recurrent hepatocellular carcinoma (HCC) with adrenal metastases, and severe chronic kidney disease.

Indexed as

biological therapycancerpsoriasisrisankizumabsevere renal impairmenttransplant organ

Identifiers

PMID40918880
PMCPMC12413925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.