ArticleCureus2025
Directional Deep Brain Stimulation Programming in Parkinson's Disease and Essential Tremor Patients: An Institution-Based Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Deep Brain Stimulation as a Rehabilitation Amplifier: A Precision-Oriented, Network-Guided Framework for Functional Restoration in Movement Disorders.Journal of clinical medicine · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deep brain stimulation (DBS) and the use of directional subsegmental stimulation have significantly advanced symptom management in patients with Parkinson's disease (PD) and essential tremor (ET). This study examines the use of directional programming in a tertiary care center. We retrospectively reviewed medical records of 12 PD patients (all with bilateral subthalamic nucleus (STN) implants) and 13 ET patients (12 with bilateral and 1 with unilateral ventral intermediate nucleus (VIM) implants) who received directional leads. Clinical parameters such as the Fahn-Tolosa-Marin (FTM) Tremor Rating Scale for ET and the Unified Parkinson's Disease Rating Scale (UPDRS) for PD were assessed before and after the procedure. Programming parameters and the reasons for switching to directional stimulation were also evaluated. Directional programming was used in 11 of 12 (92%) PD patients and 12 of 13 (92%) ET patients on at least one side. Among PD patients, 58% (7/12) used directional programming to avoid side effects, while 25% (3/12) used it to improve therapeutic benefit. Similarly, among ET patients, 64% (7/11) used directional programming to avoid side effects, and 33% (4/12) experienced improved tremor control with directional configurations. Our study demonstrates high utilization of directional programming. The findings suggest directional stimulation improves efficacy by reducing side effects and enhancing therapeutic outcomes. These results may support the early adoption of directional programming in managing PD and ET patients.
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Registered trials
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