Evidence map›Paper›PMID 40918860›Full record

ArticleCureus2025

Atypical Adenomatous Hyperplasia as a Precursor of Lung Adenocarcinoma.

Gonçalo T Lopes, Bernardo Bem, Diogo Mendonça, Marcos Oliveira, Gonçalo Samouco, Madalena Reis, Joana Ribeiro, Luís Ferreira

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gonçalo T LopesPulmonology, Unidade Local de Saúde (ULS) da Guarda, Guarda, PRT.
Bernardo BemPulmonology, Unidade Local de Saúde (ULS) da Guarda, Guarda, PRT.
Diogo MendonçaPulmonology, Unidade Local de Saúde (ULS) da Guarda, Guarda, PRT.
Marcos OliveiraPulmonology, Unidade Local de Saúde (ULS) da Guarda, Guarda, PRT.
Gonçalo SamoucoPulmonology, Unidade Local de Saúde (ULS) da Guarda, Guarda, PRT.
Madalena ReisPulmonology, Unidade Local de Saúde (ULS) da Guarda, Guarda, PRT.
Joana RibeiroPulmonology, Unidade Local de Saúde (ULS) da Guarda, Guarda, PRT.
Luís FerreiraPulmonology, Unidade Local de Saúde (ULS) da Guarda, Guarda, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary atypical adenomatous hyperplasia (AAH) is a recognized precursor lesion to pulmonary adenocarcinoma (ADC). We present the case of a 79-year-old ex-smoker in whom transthoracic needle biopsy revealed histological features suggestive of lung ADC. However, surgical resection of the lesion later demonstrated only AAH. This discrepancy likely reflects sampling variability or partial lesion regression, emphasizing the diagnostic challenges posed by small pulmonary nodules. The case highlights the importance of integrating histopathological, radiological, and clinical data, and underscores the critical role of multidisciplinary decision-making in managing preinvasive pulmonary lesions.

Indexed as

adenocarcinomaatypical adenomatous hyperplasiabiopsycancerprecursor

Identifiers

PMID40918860
PMCPMC12412263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.