ReviewCureus2025
The Complex Roles of Macrophages in Sjögren's Syndrome: A Narrative Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sjögren's syndrome (SS) is an autoimmune disease characterized by the destruction of the structure and function of exocrine glands (EGs) such as lacrimal glands (LGs) and salivary glands (SGs). During the pathogenesis, various immune cells such as lymphocytes, dendritic cells, and macrophages are activated, which together maintain the pro-inflammatory environment of the EGs. As an important immune cell linking innate and specific immunity, macrophages have both functions of phagocytosis and antigen presentation. Studies in animal models and SS patients have suggested that macrophages play an important role in the clearance of apoptotic cells and the activation of lymphocytes in the EGs of SS patients. This narrative review highlights the roles of macrophages in the development of SS, with the aim of providing a comprehensive reference for future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.