ArticleCureus2025
Spontaneous Bone Regeneration ("Phoenix Jaw" Phenomenon) Following Segmental Mandibulectomy for Stage 3 Medication-Related Osteonecrosis of the Jaw: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Segmental mandibulectomy is a valid treatment for advanced medication-related osteonecrosis of the jaw (MRONJ), but subsequent reconstruction is challenging. Spontaneous bone regeneration (SBR) following resection is exceedingly rare, particularly in the elderly. We present the case of a 63-year-old woman with stage 3 MRONJ who underwent a 60 mm segmental mandibulectomy. The defect was reconstructed with a titanium plate, with meticulous preservation of the periosteum. Over a three-year follow-up period, serial imaging demonstrated progressive and substantial bone regeneration along the plate, resulting in a robust, continuous mandibular segment without any bone grafting. This case highlights that SBR, a phenomenon metaphorically termed the "Phoenix jaw," can occur even in older patients with advanced MRONJ, challenging conventional expectations regarding bone regeneration in this patient population.
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