Evidence map›Paper›PMID 40918810›Full record

ReviewCureus2025

Anatomical Variations of the Internal Carotid Artery: A Systematic Review.

Adriano Carneiro da Costa, Lucas Rodrigues de Sousa, Vitório Augusto Alexandre Alves, Camila Ramos Martins, Laécio Leitão Batista, Antonio Alvaro Bandeira Ferraz, Nagy Habib, Moacyr Jesus Barreto de Melo Rêgo

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adriano Carneiro da CostaDepartment of Surgery, Federal University of Pernambuco, Recife, BRA.
Lucas Rodrigues de SousaDepartment of Anatomical Sciences, Federal University of Campina Grande, Campina Grande, BRA.
Vitório Augusto Alexandre AlvesDepartment of Anatomical Sciences, Federal University of Campina Grande, Campina Grande, BRA.
Camila Ramos MartinsDepartment of Family and Community Medicine, Federal University of Pernambuco, Recife, BRA.
Laécio Leitão BatistaDepartment of Diagnostic Radiology, Federal University of Pernambuco, Recife, BRA.
Antonio Alvaro Bandeira FerrazDepartment of Surgery, Federal University of Pernambuco, Recife, BRA.
Nagy HabibDepartment of Surgery & Cancer, Hammersmith Hospital, Imperial College, London, GBR.
Moacyr Jesus Barreto de Melo RêgoDepartment of Biology, Federal University of Pernambuco, Recife, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review aims to describe the anatomical variations of the internal carotid artery (ICA) and their implications for clinical practice and surgical planning. The ICA, a major vessel supplying the brain, exhibits considerable anatomical variability that can impact the safety and efficacy of procedures involving the neck region and skull base. A comprehensive search of eight databases from 2015 to 2024 yielded 379 studies, of which eight met the inclusion criteria. The reviewed studies reported common variations such as tortuosity, protrusion into the sphenoid sinus, congenital anomalies, and bony dehiscence. These findings underscore the importance of detailed preoperative imaging and thorough anatomical knowledge to reduce surgical risks and improve patient outcomes. Recognition of ICA variants remains essential for planning and performing safe and effective surgical interventions.

Indexed as

anatomical variabilitya systematic reviewinternal carotid artery (ica)neuro-surgeryskull base surgery

Identifiers

PMID40918810
PMCPMC12412266

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.