Anesthetic Management of a Pregnant Patient With Ehlers-Danlos Syndrome Undergoing Elective Cesarean Delivery: A Case Report.

Yahya M Aljuba, Daniel Shatalin, Alexander Ronenson, Aharon Grenader, Alexander Ioscovich

Abstract readCase Reports

In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yahya M AljubaDepartment of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center (Affiliated with the Hebrew University of Jerusalem), Jerusalem, ISR.

Daniel ShatalinDepartment of Anaesthesiology, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, ISR.

Alexander RonensonDepartment of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center (Affiliated with the Hebrew University of Jerusalem), Jerusalem, ISR.

Aharon GrenaderDepartment of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center (Affiliated with the Hebrew University of Jerusalem), Jerusalem, ISR.

Alexander IoscovichDepartment of Anaesthesiology, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, ISR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy in women with Ehlers-Danlos syndrome (EDS) carries elevated risks, including prematurity, hemorrhage, and maternal morbidity, posing significant anesthetic challenges. We present the case of a 36-year-old woman with classical EDS (cEDS) and multiple comorbidities, including postural orthostatic tachycardia syndrome, bronchial asthma, congenital adrenal hypoplasia, and chronic venous thrombosis, who underwent an elective cesarean section. A multidisciplinary team developed a comprehensive perioperative plan featuring ultrasound-guided spinal anesthesia, extended post-anesthesia observation, and coordinated recommendations from cardiology, hematology, endocrinology, pulmonology, and other specialties. This report emphasizes the complexity of anesthetic care in EDS pregnancies and underscores the need to tailor management to the specific EDS subtype and individual patient profile.

Indexed as

cesarean section (cs)ehlers-danlos syndromemultidisciplinary approachneuraxial anesthesiaobstetric anesthesia

Identifiers

PMID40918773

DOI10.7759/cureus.89400

PMCPMC12409755

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