Evidence map›Paper›PMID 40918760›Full record

ArticleCureus2025

Synchronous Human Papillomavirus (HPV)-Positive Oropharyngeal Carcinoma and Occult Papillary Thyroid Carcinoma: A Case Report and Review of the Literature.

Tung-Sen Tai, Yun-An Chen, Chun-Wei Huang

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tung-Sen TaiDepartment of Education, China Medical University Hospital, Taichung, TWN.
Yun-An ChenDepartment of Pathology, China Medical University Hospital, Taichung, TWN.
Chun-Wei HuangDepartment of Otolaryngology - Head and Neck Surgery, China Medical University Hospital, Taichung, TWN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synchronous malignancies involving the oropharynx and thyroid gland are rare. We report the case of a 52-year-old female diagnosed with human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) with a concurrent, clinically occult papillary thyroid carcinoma (PTC). The patient initially presented with HPV-associated OPSCC and concerns for cervical lymphadenopathy, presumed to be linked to regional metastasis from the oropharyngeal primary. However, further pathological evaluation revealed that one of the metastatic lymph nodes within the same cervical level originated from an undiagnosed PTC. This report highlights the need for careful pathological evaluation and consideration of multiple primary tumors in patients presenting with cervical lymph node metastases.

Indexed as

hpv-positive oropharyngeal squamous cell carcinomainduction chemotherapylevel ii cervical lymph node metastasisoccult thyroid carcinomapapillary thyroid carcinomasynchronous malignancytransoral robotic surgery

Identifiers

PMID40918760
PMCPMC12410417

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.