ArticleCureus2025
Significance of Inverse Planning With Variable Dose Rate and the Segment Shape Optimization in Dynamic Conformal Arcs Using the High-Definition Dynamic Radiosurgery Platform for Single Brain Metastases.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose This planning study aimed to clarify the significance of inverse planning with variable dose rate (VDR) and the segment shape optimization (SSO) in the quality and efficiency of dynamic conformal arcs (DCA) using the high-definition dynamic radiosurgery (HDRS) platform for stereotactic radiosurgery (SRS) of single brain metastases (BMs). Materials and methods Twenty clinical BMs were included, with the gross tumor volume (GTV) ranging from 0.33 cc to 48.09 cc (median: 7.05 cc). The HDRS platform included the 5-mm leaf-width, 160-leaf collimator Agility® (Elekta AB, Stockholm, Sweden) and the Monaco® planning system (Elekta AB). Prior to the main comparison, the high-precision leaf positions (HPLP) values of between five and 20 in the SSO were compared to determine which was optimal in six lesions. Using the constant dose rate (CDR) optimization as a baseline (the CDR group), the effects of changing to VDR (the VDR group), and further adding the SSO with the suitable HPLP value (the SSO group) on the DCA planning were investigated. The same prescription dose was assigned to the GTV
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