Evidence map›Paper›PMID 40918707›Full record

ArticleIndian journal of dermatology

Evaluation of Short-to-medium Term Efficacy of Guselkumab and Secukinumab in Overweight and Obese Patients with Moderate to Severe Plaque Psoriasis: A 24-Week Single-center Retrospective Study.

Xiuqiu Lin, Min Ou, Yang Li, Junjie Lin, Yunling Yan, Xiaohua Wang

Abstract read
In one paragraph

Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. IL-23 Inhibitors in Psoriasis: What Have We Learnt so Far?Journal of inflammation research · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiuqiu LinFrom the Department of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, China.
Min OuDepartment of Dermatology, Huizhou Dermatology Hospital, Huizhou, Guangdong, China.
Yang LiFrom the Department of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, China.
Junjie LinDepartment of Dermatology, Dermatology Hospital of Fuzhou, Fuzhou, Fujian, China.
Yunling YanFrom the Department of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, China.
Xiaohua WangFrom the Department of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Overweight and obesity are common in patients with psoriasis and are associated with increased disease severity and declined treatment response. Aims: To evaluate the short-to-medium term (24w) efficacy and safety of two biologics, including Guselkumab and Secukinumab, in overweight and obese patients (body mass index [BMI] ≥25 kg/m Materials and Methods: We retrospectively analyzed the data of patients with moderate to severe plaque psoriasis treated with Guselkumab or Secukinumab in Dermatology Hospital of Southern Medical University in 2020. Totally 34 and 67 patients were treated with Guselkumab and Secukinumab, respectively; the patient groups with BMI ≥25 kg/m Results: Both Guselkumab and Secukinumab demonstrated good clinical efficacy. In patients with BMI ≥25 kg/m Conclusions: Guselkumab and Secukinumab demonstrated good short-to-medium-term efficacy in Chinese patients with moderate to severe plaque psoriasis. In patients with a BMI ≥25 kg/m

Indexed as

Body mass indexGuselkumabmoderate-to-severe plaque psoriasisoverweight and obesitySecukinumab

Identifiers

PMID40918707
PMCPMC12413152

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.