Evidence map›Paper›PMID 40918607›Full record

ArticleClinical medicine insights. Arthritis and musculoskeletal disorders2025

Overlapping Connective Tissue Disease-Polymyositis and Diffuse Systemic Scleroderma: A Case Report.

Breanna Greaves, Lauren Poindexter, Hanna Jensen

Abstract readCase Reports
In one paragraph

Article in Clinical medicine insights. Arthritis and musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Breanna GreavesCollege of Medicine, University of Arkansas for Medical Sciences, Fayetteville, AR, USA.ORCID https://orcid.org/0009-0009-1961-7741
Lauren PoindexterDepartment of Physical Medicine and Rehabilitation, Division of Orthopedics and Sports Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.ORCID https://orcid.org/0009-0005-9179-8955
Hanna JensenDepartment of Surgery, University of Arkansas for Medical Sciences, Fayetteville, AR, USA.ORCID https://orcid.org/0000-0001-8487-7982

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymyositis with concomitant scleroderma is a rare, progressive condition with profound consequences if not addressed promptly. Severity and symptom presentation varies between patients, and much is unknown about how best to treat overlapping connective tissue diseases. This case discusses the rare presentation, medical evaluation, and successful treatment of a 46-year-old woman with excessive muscle atrophy, weakness, and tissue fibrosis, who was diagnosed with overlapping connective tissue disorder after extensive work up that included a muscle biopsy, skin punch biopsy, and autoantibody lab work. This patient recovered well with the use of mycophenolate mofetil demonstrating promising results for similar patients and offering insight into potential methods of evaluation and medical management. Studying cases like this one give providers more knowledge about overlapping connective tissue disease and how to best diagnose and manage them.

Indexed as

Atrophyautoantibodiesautoimmunitycase reportfibrosispolymyositisscleroderma

Identifiers

PMID40918607
PMCPMC12409035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.