Evidence map›Paper›PMID 40918559›Full record

SynthesisFrontiers in rehabilitation sciences2025

Upper limb motor recovery in chronic stroke-longitudinal aggregate analysis from control group outcomes.

Fabien Scalzo, Robert A Coker, Lauren Souders, Leo Petrossian, Kern Bhugra, Lauren Sheehan, Eric C Leuthardt, Alexander R Carter

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in rehabilitation sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fabien ScalzoKeck Data Science Institute, Pepperdine University, Malibu, CA, United States.
Robert A CokerKandu, Inc., Los Angeles, CA, United States.
Lauren SoudersKandu, Inc., Los Angeles, CA, United States.
Leo PetrossianKandu, Inc., Los Angeles, CA, United States.
Kern BhugraKandu, Inc., Los Angeles, CA, United States.
Lauren SheehanKandu, Inc., Los Angeles, CA, United States.
Eric C LeuthardtKandu, Inc., Los Angeles, CA, United States.
Alexander R CarterDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study examines the effects of regular physical activity on upper extremity motor recovery during the late subacute and chronic phases of stroke. Methods: Data were aggregated from 20 studies comprising 368 participants in control groups receiving usual care or general rehabilitation without specialized interventions. To isolate the impact of non-specific physical activity, studies involving robotics or task-specific therapies were excluded. Results: The primary outcome was the change in Fugl-Meyer Assessment of Upper Extremity (FMA-UE) motor scale. The pooled effect size for FMA-UE change was small and non-significant (Cohen's Discussion: These findings provide a quantitative benchmark for expected gains from general activity and offer a reference for interpreting outcomes in future stroke rehabilitation trials lacking control groups.

Indexed as

Fugl-Meyer assessmentmotor recoveryrehabilitationstrokeupper extremity

Identifiers

PMID40918559
PMCPMC12411421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.