Evidence map›Paper›PMID 40918209›Full record

ArticleCurrent hepatology reports2025

Hepatic Hydrothorax: A Review.

Abdellatif Ismail, Mohanad Awadalla, Suvisesh Pothuraju, Ashwani K Singal

Abstract read
In one paragraph

Article in Current hepatology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdellatif IsmailDepartment of Internal Medicine, University of Maryland Medical Center Midtown Campus, Baltimore, MD, USA.
Mohanad AwadallaBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Suvisesh PothurajuUniversity of Louisville, KY, USA.
Ashwani K SingalUniversity of Louisville, KY, USA.

Funding

Integrated therapies for alcohol use and ALD (ITAALD) Network -UofL Clinical CenterU01AA026980 · NIAAA · UNIVERSITY OF LOUISVILLE · PI CRAIG J. MCCLAIN, Ashwani K Singal · 2018 to 2026
$2.9M
NIAAA NIH HHS U01 AA026980
6 · The paper itself

Abstract

Purpose of the Review: To review epidemiology, pathogenesis, diagnosis, and management of hepatic hydrothorax. Recent Findings: Refractory hepatic hydrothorax is an independent predictor of mortality in patients with decompensated cirrhosis. Allocation of Model for End-Stage Liver Disease exception points for patients with refractory hydrothorax was found to be associated with a significant reduction in post liver transplant mortality. Summary: Hepatic hydrothorax, pleural effusion in patients with decompensated liver cirrhosis without primary pleural and cardiopulmonary pathology is associated with a high rate of morbidity and mortality. Pathogenesis is a combination of salt and water retention and unidirectional movement of fluid from the peritoneal to the thoracic cavity. Diagnosis relies on pleural fluid analysis and ruling out a primary pleural and cardiopulmonary pathology. Management is complex and requires a stepwise and multidisciplinary approach. All patients with refractory hydrothorax should be evaluated for liver transplant.

Indexed as

AscitesDecompensated CirrhosisHepatic HydrothoraxPleural EffusionSpontaneous Bacterial Pleuritis

Identifiers

PMID40918209
PMCPMC12410838

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.