Evidence map›Paper›PMID 40918195›Full record

ReviewFrontiers in cardiovascular medicine2025

The relationship between hematological parameters and coronary angiographic lesions.

Thadzia Maria de Brito Ramos, José Gildo de Moura Monteiro Júnior, Veridiana Câmara Furtado, Dário Celestino Sobral Filho

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thadzia Maria de Brito RamosPernambuco Cardiac Emergency Hospital, University of Pernambuco (PROCAPE, UPE), Recife, Brazil.
José Gildo de Moura Monteiro JúniorPernambuco Cardiac Emergency Hospital, University of Pernambuco (PROCAPE, UPE), Recife, Brazil.
Veridiana Câmara FurtadoPernambuco Cardiac Emergency Hospital, University of Pernambuco (PROCAPE, UPE), Recife, Brazil.
Dário Celestino Sobral FilhoPernambuco Cardiac Emergency Hospital, University of Pernambuco (PROCAPE, UPE), Recife, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is the most important etiology of acute myocardial infarction, which is considered an inflammatory disease with specific cellular and molecular responses. Recent research has linked hematological variables as biomarkers of the severity of coronary artery disease. Studies suggest that nucleated red blood cells (NRBCs), neutrophil to lymphocyte ratio (NLR), and mean platelet volume (MPV) may serve as components of a laboratory model or hematological scoring system for in-hospital surveillance. Atherosclerotic plaques can be graded using scoring systems, such as the SYNTAX score which is used to evaluate the complexity of coronary artery disease. However, there is an open field for research to explain the complex inflammatory mechanism of these plaques. Research has shown that inflammatory processes, such as those seen in coronary atherosclerotic disease, stimulate the bone marrow to release young and immature cells into the systemic circulation, which actively aggregate and, consequently, form thrombotic plaques. This mini review article aims to demonstrate the relationship between hematological parameters and coronary angiographic findings as potential in-hospital prognostic tools for patients with acute myocardial infarction. This expressive relationship between these hematological biomarkers and coronary atherosclerotic plaques may be a target, in addition to prognostic scores, of future therapeutic interventions.

Indexed as

coronary angiographic lesionshematological parametersmean platelet volumeneutrophil to lymphocyte rationucleated red blood cellsprognosticSYNTAX score

Identifiers

PMID40918195
PMCPMC12408698

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.