Evidence map›Paper›PMID 40918125›Full record

ArticleFrontiers in immunology2025

Identification of galectin-9 and its antibacterial function in Yellow River carp (

Li Wang, Yuanyuan Hu, Xudong Li, Ziyan Zhang, Nan Wang, Limin Chao, Chengfei Li, Pei Gao, Jinyou Ma, Lei Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Li WangCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.
Yuanyuan HuCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.
Xudong LiFishery Technology Extension Station of Henan Province, Zhengzhou, China.
Ziyan ZhangCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.
Nan WangCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.
Limin ChaoCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.
Chengfei LiCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.
Pei GaoCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.
Jinyou MaCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.
Lei WangCollege of Life Science, Henan Normal University, Xinxiang, China.
Xiaojing XiaCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Galectin-9 is a β-galactoside-binding lectin that functions as a critical pattern recognition receptor (PRR) in the host immune system, initiating immune defense responses by recognizing and binding to pathogen-associated molecular patterns (PAMPs) on the surface of microorganisms. In this study, we identified and characterized a novel galectin-9 cDNA, designated CcGal-9, from Yellow River carp ( Methods: The full-length CcGal-9 cDNA was cloned and sequenced, and its structural features were analyzed. Tissue distribution of CcGal-9 mRNA was examined by quantitative real-time PCR. Expression changes following Results: The CcGal-9 cDNA is 963 bp in length and encodes a 320-amino acid protein with two distinct carbohydrate recognition domains (CRDs), characteristic of tandem-repeat type galectins. C Discussion: These findings indicate that CcGal-9 is an important PRR in C.

Indexed as

Anti-Bacterial AgentsCarpsFish DiseasesFish ProteinsGalectinsAeromonas hydrophilaAmino Acid SequenceAnimalsCloning, MolecularGram-Negative Bacterial InfectionsPhylogenyStaphylococcus aureusAnti-Bacterial AgentsFish ProteinsGalectinsagglutinating activitybinding abilityCyprinus carpio haematopterusgalectin-9innate immunity

Identifiers

PMID40918125
PMCPMC12408316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.