Evidence map›Paper›PMID 40918029›Full record

ArticleHealth science reports2025

Anti-Müllerian Hormone Levels Are Associated With Skeletal Maturity in Adolescent Girls: A Longitudinal Study.

McKenzie L Ford, Audrey C Choh, Brandon Gonzalez, Steven R Lindheim, Frank Z Stanczyk, Lynda K McGinnis, Stefan A Czerwinski, Miryoung Lee

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

McKenzie L FordSchool of Public Health University of Texas Health Science Center at Houston Brownsville Texas USA.
Audrey C ChohSchool of Public Health University of Texas Health Science Center at Houston Brownsville Texas USA.
Brandon GonzalezCollege of Medicine University of Houston Houston Texas USA.
Steven R LindheimDepartment of Obstetrics and Gynecology, Boonshoft School of Medicine Wright State University Dayton Ohio USA.
Frank Z StanczykDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility University of Southern California Los Angeles California USA.
Lynda K McGinnisDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility University of Southern California Los Angeles California USA.
Stefan A CzerwinskiSchool of Health and Rehabilitation Sciences, College of Medicine The Ohio State University Columbus Ohio USA.
Miryoung LeeSchool of Public Health University of Texas Health Science Center at Houston Brownsville Texas USA.ORCID https://orcid.org/0000-0003-4088-304X

Funding

SUBCUTANEOUS FAT, BLOOD LIPIDS AND SUBSEQUENT OUTCOMER01HD012252 · NICHD · WRIGHT STATE UNIVERSITY · PI CZERWINSKI, STEFAN A. · 1985 to 2014
$17.3M
ADENYLYL CYCLASE G BG STIMULATION AND OPIOID TOLERANCER01DA012251 · NIDA · SUNY DOWNSTATE MEDICAL CENTER · PI GINTZLER, ALAN R · 1999 to 2011
$2.5M
NICHD NIH HHS R01 HD012252NIDA NIH HHS R01 DA012251
6 · The paper itself

Abstract

Background and Aims: The role of anti-Müllerian hormone (AMH), a potential marker of the hypothalamic-pituitary-ovarian axis, is not well established in adolescent females. Typical epidemiologic studies use secondary sexual characteristics or chronological age as predictors for AMH. Skeletal maturity, an indicator of bone development, however, has not been examined in association with AMH in adolescent females. This study aimed to examine patterns of change in AMH levels in relation to skeletal maturity in healthy adolescents from the Fels Longitudinal Study. Methods: A longitudinal study was conducted on 88 females (212 observations) between the ages of 8 and 18. AMH levels were analyzed using ELISA from stored frozen serum samples. Skeletal age from hand-wrist radiographs, as well as demographics, anthropometrics, and cardiometabolic risk factors, were included in the analysis. In the stepwise linear mixed-effects regression models, log-transformed AMH (AMH Results: Skeletal maturity significantly predicted lower AMH Conclusion: Our study showed a negative relationship between AMH and skeletal age relative to chronological age. This study highlights that AMH and skeletal maturity provide correlated information on growth and pubertal status in adolescent females.

Indexed as

adolescent girlsanti‐Müllerian hormonelongitudinal studymaturityskeletal age

Identifiers

PMID40918029
PMCPMC12411559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.