Evidence map›Paper›PMID 40917953›Full record

ArticleJournal of education and health promotion2025

Comparison of structural brain volume among sedentary normal, overweight and obese adults - A cross-sectional study.

Nikhil Raj, Rajagopal Kadavigere, Baskaran Chandrasekaran, K Vaishali, Shailesh Nayak, Sneha Ravichandran, Dilip Shettigar, Sathya Sabina Muthu, Cyril Biji, Poovitha Shruthi Paramashiva and 1 more

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Article in Journal of education and health promotion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Nikhil RajDepartment of Medical Imaging Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Rajagopal KadavigereDepartment of Radiodiagnosis and Imaging, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Baskaran ChandrasekaranDepartment of Exercise and Sports Sciences, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
K VaishaliDepartment of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Shailesh NayakDepartment of Medical Imaging Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Sneha RavichandranDepartment of Medical Imaging Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Dilip ShettigarDepartment of Medical Imaging Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Sathya Sabina MuthuDepartment of Medical Imaging Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Cyril BijiDepartment of Biostatistics, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Poovitha Shruthi ParamashivaDivision of Yoga, Centre for Integrative Medicine and Research, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Suresh SukumarDepartment of Medical Imaging Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between obesity and brain structure remains unclear, particularly in sedentary individuals. This study aimed to compare structural brain volumes among sedentary normal weight, overweight, and obese adults. MATERIALS AND

methodsIn this cross-sectional study, 102 sedentary adults (34 normal weight, 34 overweight, 34 obese) underwent brain MRI scans. Grey matter, white matter, cerebrospinal fluid, and regional brain volumes were measured. Correlations between BMI, physical activity levels, and brain volumes were analyzed within each weight group.

resultsNo significant differences in overall or regional brain volumes were found between groups. In the normal weight group, BMI positively correlated with right superior temporal gyrus (rSTG) volume (

conclusionsThis study reveals a complex, non-linear relationship between BMI and brain structure in sedentary adults. The contrasting correlations in normal weight and obese groups suggest potential BMI-related structural changes, particularly in the rSTG. These findings highlight the need for further research on the neurological impacts of obesity in sedentary populations.

Indexed as

Body mass indexbrain structuregrey mattermagnetic resonance imagingobesitysedentary behaviorwhite matter

Identifiers

PMID40917953
PMCPMC12413107

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