ArticleFrontiers in medicine2025
Pulmonary hypertension secondary to Abernethy malformation with left inferior vena cava: a case report and literature review.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Abernethy malformation is a rare condition in which the portomesenteric blood drains into systemic circulation, bypassing the liver. With advancements in imaging techniques and increased awareness of this malformation, there has been a growing number of reported cases in recent years. We present a case report and literature review in an effort to further the understanding of Abernethy malformation. Case presentation: We report a 21-year-old male presenting with pulmonary hypertension (PH) and right heart enlargement for 7 days. Portal CT angiography (CTA) revealed a vessel communication between the portal vein (PV) and the IVC, located on the left side of the abdominal aorta below the renal vein, and multiple nodular liver lesions (NLL). Finally, Abernethy malformation type II was diagnosed, which is extremely rare due to the absence of polysplenia while co-existing with anomalies of inferior vena cava (AIVC). He was discharged with stable vital signs on symptomatic therapy. Conclusion: Abernethy malformation presents with a range of clinical manifestations. It should be considered in patients with unexplained PH.
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