SynthesisFrontiers in medicine2025
Evaluating efficacy, safety, and innovation in skin care applications of essential oils: a systematic review.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and Safety of Melaleuca alternifolia (Tea Tree) Oil for Acne-A Systematic Review and Meta-Analysis.Phytotherapy research : PTR · 2026Pooled it
- GC-MS Profiling, Antioxidant and Enzyme Inhibitory Activities of Basil (Molecules (Basel, Switzerland) · 2026Article
- Antibacterial, In Vitro Anti-Inflammatory and Anti-Acne Activities ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Polymer-Based Microencapsulation ofPharmaceutics · 2026Article
- Botanical and Upcycled Bioactives for Advanced Topical Formulations: Mechanistic Pathways, Cutaneous Delivery, and Sustainability-by-Design.Pharmaceutics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Essential oils have emerged as popular natural alternatives to synthetic ingredients in cosmetic products, drawing attention for their therapeutic potential in treating skin conditions like acne, psoriasis, and atopic dermatitis. This systematic review analyzed 70 studies from the past decade across multiple databases to evaluate their effectiveness and safety in derma cosmetic applications. The research encompassed clinical trials,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.