Evidence map›Paper›PMID 40917786›Full record

ArticleOpen life sciences2025

Experimental study on salmon demineralized bone matrix loaded with recombinant human bone morphogenetic protein-2:

Lei Wang, Jing Zhu, Xiaorui Jiang, Shouyi Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lei WangOphthalmology Center, Affiliated Hospital of Weifang Medical University, Weifang, China.
Jing ZhuSchool of Laboratory Animal & Shandong Laboratory Animal Center, Institute of Laboratory Animal Science, Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong, China.
Xiaorui JiangOrthopedic Surgery Ward, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, 264000, China.
Shouyi LiStomatology Ward, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, 264000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article aims to explore the effects of salmon demineralized bone matrix (DBM) combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) on bone formation. Salmon DBM, with its high water absorption capacity, was used to construct a composite material with rhBMP-2 under pH 7.0 and optimal temperature conditions. The compound effects of the composite material were evaluated by measuring its mechanical strength, microstructure, and biocompatibility through scanning electron microscopy and cell culture experiments. The effect of rhBMP-2 within the composite was assessed by

Indexed as

bone morphogenetic protein-2calcium depositiondecalcified bone matrixosteogenesis

Identifiers

PMID40917786
PMCPMC12412370

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.