Evidence map›Paper›PMID 40917780›Full record

ArticleOpen life sciences2025

Combination of immunotherapy and whole-brain radiotherapy on prognosis of patients with multiple brain metastases: A retrospective cohort study.

Pengwei Yan, Changzhai Wang, Duixian Tuoligan, Aji Kabinuer, Sheng Li, Xue Song, Huanfeng Zhu

Abstract read
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pengwei YanDepartment of Radiation Oncology, Jiangsu Cancer Hospital, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Institute of Cancer Research, No. 42 Baiziting, Xuanwu District, Nanjing, 210009, P.R. China.
Changzhai WangDepartment of Radiation Oncology, the Affiliated Kezhou People's Hospital of Nanjing Medical University & People's Hospital of Kizilesu Kirgiz Autonomous Prefecture, Kezhou, 845350, Xinjiang, P.R. China.
Duixian TuoliganDepartment of Radiation Oncology, the Affiliated Kezhou People's Hospital of Nanjing Medical University & People's Hospital of Kizilesu Kirgiz Autonomous Prefecture, Kezhou, 845350, Xinjiang, P.R. China.
Aji KabinuerDepartment of Radiation Oncology, the Affiliated Kezhou People's Hospital of Nanjing Medical University & People's Hospital of Kizilesu Kirgiz Autonomous Prefecture, Kezhou, 845350, Xinjiang, P.R. China.
Sheng LiDepartment of Radiation Oncology, the Affiliated Kezhou People's Hospital of Nanjing Medical University & People's Hospital of Kizilesu Kirgiz Autonomous Prefecture, Kezhou, 845350, Xinjiang, P.R. China.
Xue SongDepartment of Radiation Oncology, Jiangsu Cancer Hospital, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Institute of Cancer Research, No. 42 Baiziting, Xuanwu District, Nanjing, 210009, P.R. China.
Huanfeng ZhuDepartment of Radiation Oncology, Jiangsu Cancer Hospital, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Institute of Cancer Research, No. 42 Baiziting, Xuanwu District, Nanjing, 210009, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain metastases (BMs) usually occur in the advanced stage of cancers with a poor prognosis. This study aimed to compare the clinical efficacy and effects on cognitive function of immunotherapy combined with whole brain radiotherapy (WBRT) and immunotherapy combined with WBRT plus sequential integrated boost (SEB) in the treatment of multiple BMs. A total of 57 patients diagnosed with BMs were included in Kezhou People's Hospital Affiliated to Nanjing Medical University between 2021 and 2023. Patients were allocated into the WBRT group (

Indexed as

brain metastasesimmunotherapyintegrated boostwhole brain radiotherapy

Identifiers

PMID40917780
PMCPMC12412368

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.