ArticleNature. Mental health2025
Cognitive and Global Morphometry Trajectories as Predictors of Youth Persistent Distressing Psychotic-Like Experiences.
Article in Nature. Mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Untangling relationships between cognitive development and child and adolescent mental health: Findings from the ABCD Study.Developmental cognitive neuroscience · 2026Review
- The Adolescent Brain Cognitive Development (ABCD) Study: Ten years of statistical and methodological contributions.Developmental cognitive neuroscience · 2026Article
- Transdiagnostic divergent neural development of reward anticipation in early adolescents at risk for depression and psychosis.Developmental cognitive neuroscience · 2026Article
- Disentangling Environmental and Genetic Influences on Associations Between Childhood Bullying Victimization and Psychotic-Like Experiences.medRxiv : the preprint server for health sciences · 2026Article
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Authors and funding
11 authors.
Funding
Abstract
Psychotic-like experiences (PLEs) may arise from genetic and environmental risk leading to worsening cognitive and morphometry metrics over time, which in turn lead to worsening PLEs. Analyses used three waves of unique longitudinal Adolescent Brain Cognitive Development Study data (ages 9-13) to test whether changes in cognition and global morphometry metrics attenuate associations between genetic and environmental risk with persistent distressing PLEs. Multigroup univariate latent growth models examined three waves of cognitive metrics and global morphometry separately for three PLE groups: persistent distressing PLEs (n=356), transient distressing PLEs (n=408), and low-level PLEs (n=7901). Persistent distressing PLEs showed greater decreases (i.e., more negative slopes) of cognition and morphometry metrics over time compared to those in low-level PLE groups. Analyses also provided novel evidence for extant theories that worsening cognition and global morphometry metrics may partially account for associations between environmental risk with persistent distressing PLEs.
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